METHODS DEVELOPED IN THE COREY GROUP

 SINCE 1950

This page displays methods developed in the Corey group since 1950. The search engine boxes are connected with the "AND" logical operator which means that the more fields you choose to specify, the narrower your search will become. You may click on the hyperlinked article numbers listed after "Relevant Publication Link" below; the corresponding article will be displayed.
 

There are 17 methods listed in this database.

 

Descriptive Title:   Year of disclosure:
Affected functional group:   Newly formed functional group:
Reagents/Catalysts:   Method keyword:

METHODS

Protection-Deprotection of Indoles (2003)

 Selected example:

Affected Functional Group: indole
Newly Formed Functional Group: NA
Reagents and/or Catalysts: 4-methyl-1,2,4-triazoline-3,5-dione (MTAD)
Method Keyword(s): indole protection
Relevant Publication Link(s) : 954             

[these numbers correspond to the article numbers in Professor Corey's publication list]

 

 

Synthesis and intramolecular cyclopropanation with diazoesters (1984)

 Selected example:

Affected Functional Group: NA
Newly Formed Functional Group: NA
Reagents and/or Catalysts: glyoxylic acid chloride p-toluenesulfonylhydrazone, bis(N-tert-butylsalicylaldiminato)copper (II)
Method Keyword(s): cyclopropanation, diazoester,
Relevant Publication Link(s) : 557             

[these numbers correspond to the article numbers in Professor Corey's publication list]

 

 

t-Butoxymethyllithium as a hydroxymethyl anion equivalent (1983)

 Selected example:

Affected Functional Group: NA
Newly Formed Functional Group: NA
Reagents and/or Catalysts: tert-butyl methyl ether, potassium tert-butoxide-sec-butyllithium, lithium bromide
Method Keyword(s): metallation,
Relevant Publication Link(s) : 510             

[these numbers correspond to the article numbers in Professor Corey's publication list]

 

 

Zinc or Magnesium Triflate-Catalyzed Thioketalization (1983)

 Selected example:

Affected Functional Group: ketone
Newly Formed Functional Group: thioketal
Reagents and/or Catalysts: magnesium triflate or zinc triflate
Method Keyword(s): protecting group
Relevant Publication Link(s) : 492             

[these numbers correspond to the article numbers in Professor Corey's publication list]

 

 

Formation of α,β-Epoxy Systems From β-Peroxy Carbon Free Radicals (1983)

 Selected example:

Affected Functional Group: peroxymercurial
Newly Formed Functional Group: epoxide
Reagents and/or Catalysts: Mercuric trifluoroacetate, borohydride
Method Keyword(s): Radical cyclization, reduction
Relevant Publication Link(s) : 511             

[these numbers correspond to the article numbers in Professor Corey's publication list]

 

 

Simple Synthesis of Alkoxy- and Aryloxymethyllithium Reagents (1983)

 Selected example:

Affected Functional Group: NA
Newly Formed Functional Group: NA
Reagents and/or Catalysts: Tin (II) chloride – lithium bromide complex
Method Keyword(s): metallation
Relevant Publication Link(s) : 509             

[these numbers correspond to the article numbers in Professor Corey's publication list]

 

 

Radical cyclization of ketones forming cyclopentanols (1983)

 Selected example:

Affected Functional Group: ketone
Newly Formed Functional Group: alcohol
Reagents and/or Catalysts: zinc (powder), trimethylchlorosilane
Method Keyword(s): reduction, radical cyclization
Relevant Publication Link(s) : 506             

[these numbers correspond to the article numbers in Professor Corey's publication list]

 

 

Flexible annulation forming cyclohexenones (1978)

 Selected example:

Affected Functional Group: NA
Newly Formed Functional Group: NA
Reagents and/or Catalysts: α-lithio N,N-dimethylhydrazone cuprate
Method Keyword(s): annulation, cyclization, conjugate addition
Relevant Publication Link(s) : 387             

[these numbers correspond to the article numbers in Professor Corey's publication list]

 

 

Oxidative cationic cyclizations using PCC (1978)

 Selected example:

Affected Functional Group: alcohol
Newly Formed Functional Group: enone
Reagents and/or Catalysts: pyridinium chlorochromate
Method Keyword(s): oxidation
Relevant Publication Link(s) : 380             

[these numbers correspond to the article numbers in Professor Corey's publication list]

 

 

Annulation processes based on benzothiazoles (1978)

 Selected example:

Affected Functional Group: NA
Newly Formed Functional Group: NA
Reagents and/or Catalysts: benzothiazole
Method Keyword(s): annulation, cyclization, aldehyde protection,
Relevant Publication Link(s) : 370             

[these numbers correspond to the article numbers in Professor Corey's publication list]

 

 

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